About Us
Christopher J. Welch, Ph.D.
Scientific Consultant Specializing in:
- Separation Science, Chirality and Stereochemistry
- Pharmaceutical Process R&D
- High Throughput Experimentation
- Pharmaceutical & Biopharmaceutical Industry
- New Research Technologies
- Strategic Planning
- Scientific Publication and Communication Strategy
Biographical Sketch
Christopher J. Welch is a principal with Welch Innovation, LLC, an independent research and consulting firm. He serves as the Executive Director of the Indiana Consortium for Analytical Sciences and Engineering (ICASE), a joint venture between Purdue, Notre Dame and Indiana University (link). Chris also serves as a member of the Scientific Advisory Board for Snapdragon Chemistry, Inc. and Enantiosense, LLC. Dr. Welch has worked in a variety of fields within the chemical industry, including discovery synthesis of agrochemicals (Velsicol-Sandoz), development of reagents for improved immunodiagnostic assays (Abbott Laboratories), development and commercialization of chromatographic stationary phases, reagents and enantioselective catalysts within a small chemical business environment (Regis Technologies) invention and application of new purification, analysis and high throughput experimentation technologies for pharmaceutical process research (Merck & Co.) and as a Science Advisor for the US FDA. While at Merck, Dr. Welch created and administered Merck's postdoctoral research fellows program and managed a multi-million-dollar fund and research network that identified, evaluated and acquired more than 300 new enabling technologies for pharmaceutical discovery and development. Dr. Welch has authored more than 250 scientific publications and patents. He is co-founder of the journal, Enantiomer, and a member of the editorial advisory board for the journals, Chirality, ACS Central Science and the Russian Journal of Physical Chemistry. Chris is past chair of the ACS Division of Organic Chemistry (ORGN), a member of the Executive Committee for the International Symposia on Chirality and the PittCon Program Resource Team, vice-chair of Pacifichem 2020 and co-founder of the Enabling Technologies Consortium (ETC). Honors and awards include the NJCG Award for Excellence in Chromatography (2004), the PACS Activated Carbon Hall of Fame award (2007), MRL Presidents Award for Environmental Achievement (2009), Microsoft Life Science Innovation Award (2010), Fellow of the American Chemical Society (2010), Fellow of the American Association for the Advancement of Science, AAAS (2013) the Chirality Medal (2015), the University of Nebraska Chemistry Industrial Award (2016) the EAS Award for Outstanding Achievement in Separation Science (2017) and the Uwe Neue Award in Separation Science (2019)
Recent Publications
For a complete listing, see the GoogleScholar page here.
Fragmentation of polyfunctional compounds recorded using automated high-throughput desorption electrospray ionization and as compared to expert predictions, MyPhuong T. Le, Nicolás M. Morato, Andreas Kaerner Christopher, J. Welch and R. Graham Cooks, Journal of the American Society for Mass Spectrometry, 2021, in press..
An Assessment of the Material Measurmeent Laboratory at the National Institute of Standards and technology, Fiscal Year, 2020, The National Academies Press, Wasshington, DC, Elsa Reichmanis, Ilhan A. Aksay, Nancy L. Allbriton, Kevin R. Anderson, L. Brock, Dennis E. Discher, Thomas W. Eager, Robert E. Fontana, Jr., Eric E. Fullerton, Amit Goyal, Olivia A. Graeve, Jennie C. Henter-Cevera, Carl Kesselman, Wook Kim, Mukul Kumar, Michael R. Ladisch, Steven H. McKnight, Phillip M. Neches, Krishna Rajan, Ann Beal Salamone, Wendy Shaw, Subhash Singhal, Michael G. Spencer, Kathleen C. Taylor, Christopher J. Welch, The National Academies Press, 2021, link.
Next-Generation TLC: A Facile and Quantitative Platform for Parallel Spotting and Imaging, Alexander A. Boulgakov, Sarah Moor, Hyun Hwa Jo, Pedro Metola, Leo A. Joyce, Edward M. Marcotte, Christopher J. Welch, and Eric V. Anslyn, Journal of Organic Chemistry, available online, 2020, link, DOI: 10.1021/acs.joc.0c00349.
Cross-Pharma Collaboration on the Development and Evaluation of a New Mid-Scale Preparative Supercritical Fluid Chromatography (SFC) Instrument, Mirlinda Biba, Mengling Wong, Anne Akin, Eric T. Manning, Lisa Schaffter, Larry Miller, Yingru Zhang, Bill Farrell, Jimmy O. DaSilva, Lisa Nogle, Benjamin Hritzko, Frank Riley, Robert P. DePianta, Kevin Barry, Amy Gao, Eric Seest, Meenashki Goel, Loanne Chung, James Paulson, Heewon Leek, Douglas B. Moor, Shuping Dong, William Leister, Nobumitsu Fukushima, Andy Sasaki, Timothy Lee, Takayuki Iriki, Masayuki Nishimura, Masami Tomita, Michiaki Owa, Katsuhiro Tanaka, Tomohiro Shagawa, Thomas J. Moran, Takeshi Bamba, Christopher J. Welch, available online, Org. Proc. R & D, 2020.
282) Preview of Topics at HPLC 2020, Part I: Addressing Industry Separation Science Needs through Research Collaborations with Academia, Christopher J. Welch, LC-GC, 2020, available online, link.
William H Pirkle: Stereochemistry Pioneer, Christopher J. Welch, Chirality, 2020, available online, link.
Preview of Topics at HPLC 2020, Part I: Addressing Industry Separation Science Needs through Research Collaborations with Academia, Christopher J. Welch, LC-GC, 2020, available online, link.
Mass Activated Droplet Sorting (MADS) Enables High Throughput Screening of Enzymatic Reactions at Nanoliter Scale, Daniel A. Holland-Moritz, Michael Wismer, Benjamin F. Mann, Iman Farasat, Paul Devine, Erik D. Guetschow, Ian Mangion, Christopher J. Welch, Jeffrey C. Moore, Shuwen Sun and Robert T. Kennedy, available online, Angewandte Chemie, 2020, link.
Under Pressure to Perform: Impact of UHPLC Technology on Pharmaceutical Research and Development, LC-GC North America 37, June 2019, 481-484, link
High Throughput Analysis Enables High Throughput Experimentation in Pharmaceutical Process Research, available online, Reaction Chemistry & Engineering, 2019, link.
Optical Chirality Sensing with a Stereodynamic Aluminum Biphenolate Probe, De los Santos, Zeus; Joyce, Leo; Welch, Christopher; Wolf, Christian, Journal of Organic Chemistry 84, 4639–4645, 2019, link.
In the News
Analytical Chemistry of Beer and Brewing, link
The Science Behind the Beer and Brewing Industry, Medical and Life Science News, link.
Preview of Topics at HPLC 2020, Part I: Addressing Industry Separation Science Needs through Research Collaborations with Academia, Christopher J. Welch, LC-GC, 2020, available online, link.
The Intelligent HPLC: How AI Can Transform Chromatography Workflows, C&EN White Paper, Oct 2019 link.
The Future of Chromatographic Method Development in Pharma, interview by Laura Bush, LC-GC online, Sept 2018, link.
Happy National DNA Day, April 25, 2019, link.