About Us

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Christopher J. Welch, Ph.D.

Scientific Consultant Specializing in:

- Separation Science, Chirality and Stereochemistry

- Pharmaceutical Process R&D

- High Throughput Experimentation

- Pharmaceutical & Biopharmaceutical Industry

- New Research Technologies

- Strategic Planning

- Scientific Publication and Communication Strategy

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Biographical Sketch

Christopher J. Welch is a principal with Welch Innovation, LLC, an independent research and consulting firm.  He serves as the Executive Director of the Indiana Consortium for Analytical Sciences and Engineering (ICASE), a joint venture between Purdue, Notre Dame and Indiana University (link).  Chris also serves as a member of the Scientific Advisory Board for Snapdragon Chemistry, Inc.  and Enantiosense, LLC.  Dr. Welch has worked in a variety of fields within the chemical industry, including discovery synthesis of agrochemicals (Velsicol-Sandoz), development of reagents for improved immunodiagnostic assays (Abbott Laboratories), development and commercialization of chromatographic stationary phases, reagents and enantioselective catalysts within a small chemical business environment (Regis Technologies) invention and application of new purification, analysis and high throughput experimentation technologies for pharmaceutical process research (Merck & Co.) and as a  Science Advisor for the US FDA.  While at Merck, Dr. Welch created and administered Merck's postdoctoral research fellows program and managed a multi-million-dollar fund and research network that identified, evaluated and acquired more than 300 new enabling technologies for pharmaceutical discovery and development.  Dr. Welch has authored more than 250 scientific publications and patents.   He is co-founder of the journal, Enantiomer, a member of the editorial advisory board for the journals, Chirality, Journal of the Korean Chemical Society, Chemistry World and ACS Central Science.  Chris is past chair of the ACS Division of Organic Chemistry (ORGN), a member of the Executive Committee for the International Symposia on Chirality and the PittCon Program Resource Team, vice-chair of Pacifichem 2020 and co-founder of the Enabling Technologies Consortium (ETC).  Honors and awards include the NJCG Award for Excellence in Chromatography (2004), the PACS Activated Carbon Hall of Fame award (2007), MRL Presidents Award for Environmental Achievement (2009), Microsoft Life Science Innovation Award (2010), Fellow of the American Chemical Society (2010), Fellow of the American Association for the Advancement of Science, AAAS (2013) the Chirality Medal (2015), the University of Nebraska Chemistry Industrial Award (2016) the EAS Award for Outstanding Achievement in Separation Science (2017) and the Uwe Neue Award in Separation Science (2019).

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Recent Publications

For a complete listing, see the GoogleScholar page here.


 Preview of Topics at HPLC 2020, Part I: Addressing Industry Separation Science Needs through Research Collaborations with Academia, Christopher J. Welch, LC-GC, 2020, available online, link

  

Mass Activated Droplet Sorting (MADS) Enables High Throughput Screening of Enzymatic Reactions at Nanoliter Scale, Daniel A. Holland-Moritz, Michael Wismer, Benjamin F. Mann, Iman Farasat, Paul Devine, Erik D. Guetschow, Ian Mangion, Christopher J. Welch, Jeffrey C. Moore, Shuwen Sun and Robert T. Kennedy, available online, Angewandte Chemie, 2020 (link).


Under Pressure to Perform: Impact of UHPLC Technology on Pharmaceutical Research and Development, LC-GC North America 37, June 2019, 481-484 (link)


High Throughput Analysis Enables High Throughput Experimentation in Pharmaceutical Process Research, available online, Reaction Chemistry & Engineering, 2019 (link).


Optical Chirality Sensing with a Stereodynamic Aluminum Biphenolate Probe, De los Santos, Zeus; Joyce, Leo; Welch, Christopher; Wolf, Christian, Journal of Organic Chemistry 84, 4639–4645, 2019 (link).


 Modeling and predicting chiral stationary phase enantioselectivity: An efficient random forest classifier using an optimally balanced training dataset and an aggregation strategy, Patrick Piras, Robert Sheridan, Christopher J. Welch and Christian Roussel, J. Sep. Sci.41, 1365-1375, 2018 (link).


In the News

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The Science Behind the Beer and Brewing Industry, Medical and Life Science News, link.


 Preview of Topics at HPLC 2020, Part I: Addressing Industry Separation Science Needs through Research Collaborations with Academia, Christopher J. Welch, LC-GC, 2020, available online, link


The Intelligent HPLC: How AI Can Transform Chromatography Workflows, C&EN White Paper, Oct 2019 link.


The Future of Chromatographic Method Development in Pharma, interview by Laura Bush, LC-GC online, Sept 2018, link.


Happy National DNA Day, April 25, 2019, link.  


Contact Us

Drop us a line!

Better yet, see us in person!

Pittcon 2020, Chicago, IL, March 1-5:

- Networking Session on Industry-University Collaborations in Measurement Science: Collaborative Development of Enabling Technologies for Industry (with Paul Bohn, March 2, 2:00 pm, W185D)

- Ultrahigh Performance Liquid Chromatography: Key Enabling Technology for Pharmaceutical Discovery, Development and Manufacturing (March 3, 1:35 pm, W181A)


Chirality 2020, Tianjin, China, Aug 20-23, 2020 link