About Us
Christopher J. Welch, Ph.D.
Scientific Consultanting in:
- Separation Science, Chirality and Stereochemistry
- Pharmaceutical Process R&D
- High Throughput Experimentation
- Pharmaceutical & Biopharmaceutical Industry
- New Research Technologies
- Strategic Planning
- Scientific Publication and Communication Strategy
Biographical Sketch
Christopher J. Welch is a principal with Welch Innovation, LLC, an independent research and consulting firm. He serves as the Executive Director of the Indiana Consortium for Analytical Sciences and Engineering (ICASE), a joint venture between Purdue, Notre Dame and Indiana University (link). Chris also serves as a member of the Scientific Advisory Board for Snapdragon Chemistry, Inc. and Enantiosense, LLC. Dr. Welch has worked in a variety of fields within the chemical industry, including discovery synthesis of agrochemicals (Velsicol-Sandoz), development of reagents for improved immunodiagnostic assays (Abbott Laboratories), development and commercialization of chromatographic stationary phases, reagents and enantioselective catalysts within a small chemical business environment (Regis Technologies) invention and application of new purification, analysis and high throughput experimentation technologies for pharmaceutical process research (Merck & Co.) and as a Science Advisor for the US FDA. While at Merck, Dr. Welch created and administered Merck's postdoctoral research fellows program and managed a multi-million-dollar fund and research network that identified, evaluated and acquired more than 300 new enabling technologies for pharmaceutical discovery and development. Dr. Welch has authored more than 250 scientific publications and patents. He is co-founder of the journal, Enantiomer, and a member of the editorial advisory board for the journals, Chirality and ACS Central Science. Chris is past chair of the ACS Division of Organic Chemistry (ORGN), a member of the Executive Committee for the International Symposia on Chirality and the PittCon Program Resource Team, vice-chair of Pacifichem 2020 and co-founder of the Enabling Technologies Consortium (ETC). Honors and awards include the NJCG Award for Excellence in Chromatography (2004), the PACS Activated Carbon Hall of Fame award (2007), MRL Presidents Award for Environmental Achievement (2009), Microsoft Life Science Innovation Award (2010), Fellow of the American Chemical Society (2010), Fellow of the American Association for the Advancement of Science, AAAS (2013) the Chirality Medal (2015), the University of Nebraska Chemistry Industrial Award (2016) the EAS Award for Outstanding Achievement in Separation Science (2017) and the Uwe Neue Award in Separation Science (2019)
Recent Publications
For a complete listing, see the GoogleScholar page here.
Quantitation of Trastuzumab and an Antibody to SARS-CoV-2 in Minutes Using Affinity Membranes in 96-Well Plates, Hui Yin Tan, Ivan Budyak, Brandy Verhalen, Christopher J. Welch, Merlin L. Bruening, Analytical Chemistry 94, 884-891, link.
Fluorometric and colorimetric quantification techniques with autonomously and reversibly stalling catalytic signal amplification, X Bu, J Jo, K Koide, MP Tracey, CJ Welch, 2022, US Patent 11,220,703
Fragmentation of Polyfunctional Compounds Recorded Using Automated High-Throughput Desorption Electrospray Ionization, MyPhuong T. Le, Nicolás M. Morato, Andreas Kaerner Christopher, J. Welch and R. Graham Cooks, Journal of the American Society for Mass Spectrometry, 2021, 32, 8, 2261–2273, link.
An Assessment of the Material Measurmeent Laboratory at the National Institute of Standards and technology, Fiscal Year, 2020, The National Academies Press, Wasshington, DC, Elsa Reichmanis, Ilhan A. Aksay, Nancy L. Allbriton, Kevin R. Anderson, L. Brock, Dennis E. Discher, Thomas W. Eager, Robert E. Fontana, Jr., Eric E. Fullerton, Amit Goyal, Olivia A. Graeve, Jennie C. Henter-Cevera, Carl Kesselman, Wook Kim, Mukul Kumar, Michael R. Ladisch, Steven H. McKnight, Phillip M. Neches, Krishna Rajan, Ann Beal Salamone, Wendy Shaw, Subhash Singhal, Michael G. Spencer, Kathleen C. Taylor, Christopher J. Welch, The National Academies Press, 2021, link.
Next-Generation TLC: A Facile and Quantitative Platform for Parallel Spotting and Imaging, Alexander A. Boulgakov, Sarah Moor, Hyun Hwa Jo, Pedro Metola, Leo A. Joyce, Edward M. Marcotte, Christopher J. Welch, and Eric V. Anslyn, Journal of Organic Chemistry, available online, 2020, link, DOI: 10.1021/acs.joc.0c00349.
Cross-Pharma Collaboration on the Development and Evaluation of a New Mid-Scale Preparative Supercritical Fluid Chromatography (SFC) Instrument, Mirlinda Biba, Mengling Wong, Anne Akin, Eric T. Manning, Lisa Schaffter, Larry Miller, Yingru Zhang, Bill Farrell, Jimmy O. DaSilva, Lisa Nogle, Benjamin Hritzko, Frank Riley, Robert P. DePianta, Kevin Barry, Amy Gao, Eric Seest, Meenashki Goel, Loanne Chung, James Paulson, Heewon Leek, Douglas B. Moor, Shuping Dong, William Leister, Nobumitsu Fukushima, Andy Sasaki, Timothy Lee, Takayuki Iriki, Masayuki Nishimura, Masami Tomita, Michiaki Owa, Katsuhiro Tanaka, Tomohiro Shagawa, Thomas J. Moran, Takeshi Bamba, Christopher J. Welch, available online, Org. Proc. R & D, 2020.
William H Pirkle: Stereochemistry Pioneer, Christopher J. Welch, Chirality, 2020, available online, link.
In the News
The Analytical Scientist Power List 100 for 2021 link
Analytical Chemistry of Beer and Brewing, link
The Science Behind the Beer and Brewing Industry, Medical and Life Science News, link.
Preview of Topics at HPLC 2020, Part I: Addressing Industry Separation Science Needs through Research Collaborations with Academia, Christopher J. Welch, LC-GC, 2020, available online, link.
Happy National DNA Day, April 25, 2019, link.